Rams vs. 49ers odds, line: 2020 NFL picks, Week 12 predictions from advanced computer model

The San Francisco 49ers and the Los Angeles Rams are set to square off in an NFC West matchup at 4:05 p.m. ET on Sunday at SoFi Stadium. Los Angeles is 7-3 overall and 4-0 at home, while the 49ers are 4-6 overall and 3-2 on the road. The Niners won the first meeting between the teams in Week 6, 24-16. 

Los Angeles is favored by 6.5 points in the latest Rams vs. 49ers odds from William Hill Sportsbook, and the over-under is set at 44.5. Before entering any 49ers vs. Rams picks, you’ll want to see the NFL predictions from the model at SportsLine.

The model, which simulates every NFL game 10,000 times, is up more than $7,800 for $100 players on top-rated NFL picks since its inception five-plus years ago. It is a sizzling 19-10 on top-rated NFL picks this season, returning almost $800. The model also enters

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Patriots vs. 49ers odds, line: 2020 NFL picks, Week 7 predictions from proven computer model

The New England Patriots will take on the San Francisco 49ers at 4:25 p.m. ET on Sunday at Gillette Stadium. New England is 2-3 overall and 2-1 at home, while San Francisco is 3-3 overall and 2-0 on the road. The Patriots have lost three of their past four games. The 49ers have lost two of their past three games. 

New England is favored by 2.5 points in the latest Patriots vs. 49ers odds from William Hill, and the over-under is set at 44.5. Before entering any 49ers vs. Patriots picks, you’ll want to see the NFL predictions from the model at SportsLine.

The model, which simulates every NFL game 10,000 times, is up over $7,800 for $100 players on top-rated NFL picks since its inception five-plus years ago. It’s off to a strong 14-6 roll on top-rated NFL picks this season. The model also enters Week 7 on an

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