Research team develops software that cuts time, cost from gene sequencing

gene
Credit: CC0 Public Domain

A team of Johns Hopkins University researchers has developed a new software that could revolutionize how DNA is sequenced, making it far faster and less expensive to map anything from yeast genomes to cancer genes.


The software, detailed in a paper published in Nature Biotechnology, can be used with portable sequencing devices to accelerate the ability to conduct genetic tests and deliver diagnoses outside of labs. The new technology targets, collects and sequences specific genes without sample preparation and without having to map surrounding genetic material like standard methods require.

“I think this will forever change how DNA sequencing is done,” said Michael C. Schatz, a Bloomberg Distinguished Associate Professor of Computer Science and Biology and senior author of the paper.

The new process shrinks the time it takes to profile gene mutations, from 15 days or more to just three. That allows scientists to understand

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Sana CEO reveals details about stealthy gene therapy startup that has raised more than $700M

Luke Timmerman interviews Sana Biotechnology CEO Steve Harr at the GeekWire Summit this week.

Sana Biotechnology CEO Steve Harr shed more light on one of most secretive, heavily funded startups in Seattle and the global biotech industry — detailing its plans to create tools that replace and repair human body cells, with the potential to treat various diseases and create new medicines.

Harr spoke with biotechnology journalist Luke Timmerman, founder of The Timmerman Report, this week at the GeekWire Summit. Sana raised more than $700 million this summer in one of the largest venture financing deals in the life sciences industry and one of the biggest rounds on record in Seattle.

Founded in 2019, the 250-person company has an ambitious goal of both repairing cells in the body (gene therapy) and also replacing damaged cells (cell therapy). It’s led by several former executives from Juno Therapeutics, another Seattle biotech company

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Join Gene Kim, Michael Nygard, Elisabeth Hendrickson, and 54 Other Software Leaders at QCon Plus

QCon Plus, the virtual conference for senior software engineers and architects that covers the trends, best practices, and solutions leveraged by the world’s most innovative software organizations is less than 2 weeks away. Save your spot now and take advantage of the limited early bird tickets.  

Taking place between November 4-20, QCon Plus is designed to help you accelerate your learning with thoughtfully designed, shorter, technical sessions over 3 weeks featuring 54 speakers, 4 keynotes, 18+ facilitated peer sharing sessions, and 6 open space sessions. On-demand access to presentations will be available to all registered attendees after the event. 

This is your chance to:

  • Discover hard-learned architectural lessons on scalability, reliability, throughput, and performance from successful companies in our industry
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